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Anaphylaxis and Anesthesia
Perioperative anaphylaxis can be a life-threatening clinical syndrome involving multiple organ systems. The most commonly involved agents in perioperative anaphylaxis are NMBAs, latex,
and antibiotics. Anaphylaxis usually occurs shortly after induction, with NMBAs or antibiotics being primarily
involved, but anaphylaxis may occur any time with all potentially
allergenic agents. Dyes, hypnotic agents, local anesthetics, opioids,
colloids, aprotinin, protamine, chlorhexidine, and contrast agents are less
frequently involved. Latex-induced anaphylaxis usually occurs up to 30–60
min after the beginning of the surgery but may occur immediately.
External Links
Seattle Children's Hospital Anaphylaxis Clinical Pathway